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During the Black Friday sales in November last year (2016), I bought the NIOD Set which included the full sized version of NIOD Copper Amino Isolate Serum 1.00% (CAIS), Multi-Molecular Hyaluronic Complex (MMHC), Sanskrit Saponins and Superoxide Dismutase Saccharide Mist (SDSM). It was too good a deal to pass up since the set costs US$100 and the normal price of all these products combined is US$265. Anyway, I think that Deciem got overwhelmed with their Black Friday orders and it wasn’t until January 2017 (!) that I actually received my order. I’ve been using these products on and off since then and I’m a bit on the fence about them. I’ll explain why in a bit. For now, let’s just check out their ingredients, shall we?

NIOD Copper Amino Isolate Serum 1.00% (CAIS) Ingredients


Aqua (Water), Copper Tripeptide-1, Sodium Hyaluronate Crosspolymer, Pentylene Glycol, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin.


Aqua (Water), Glycerin, Dimethyl Isosorbide, Decapeptide-22, Oligopeptide-78, Palmitoyl Decapeptide-21, Zinc Palmitoyl Nonapeptide-14, Myristoyl Nonapeptide-3, Copper Lysinate/Prolinate, Methylglucoside Phosphate, Hydrolyzed Wheat Protein, Arginine, Pentylene Glycol, Xanthan Gum, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Ethoxydiglycol, Caprylyl Glycol, Glyceryl Caprylate, Phenylpropanol, Phenoxyethanol, Chlorphenesin.

NIOD Multi-Molecular Hyaluronic Complex (MMHC) Ingredients

Aqua (Water), Hydrolyzed Yeast Extract, Sodium Hyaluronate Crosspolymer, Dimethyl Isosorbide, Glycerin, Sodium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Tamarindus Indica Seed Gum, Tremella Fuciformis Sporocarp Extract, Sodium Butyroyl Hyaluronate, Myristoyl Nonapeptide-3, Polyacrylate Crosspolymer-6, Ceratonia Siliqua Gum, N-Acetyl-D-Glucosamine-6-Phosphate Disodium Salt, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Betaine, Trisodium Ethylenediamine Disuccinate, Ethylhexylglycerin, Cetyl Hydroxyethylcellulose, Pentylene Glycol, Potassium Sorbate, Citric Acid, Sodium Benzoate, Lecithin, Magnesium Chloride, PPG-26-Buteth-26, PEG-40 Hydrogenated Castor Oil, Polyglucuronic Acid, Chlorphenesin, Phenoxyethanol.

How does the NIOD CAIS 1.00% fare?

NIOD claims that the CAIS 1.00% serum offers a highly-focused effort to maintain healthy-looking skin and a novel approach to target all signs of skin aging indirectly. This concentrated serum departs from the traditional thinking of addressing visible aspects of skin ageing individually and instead forms a foundation to respect skin health. This product claims to do so through the 1.0% pure Copper Tripeptide-1 (GHK-Cu) mixed with a specialised activator concentration targets signs of skin aging, including visible textural damage, uneven tone, visibly enlarged pores and a general lack of a visibly healthy radiance normally present in younger skin. In short, the skin will look younger starting within 5 days with continued visible improvements with continued use.

This is a very runny watery serum which is blue in colour due to the copper peptides in it. I would suggest that you drop the serum directly onto your face after using the pipette to suck up the product. If you place it in your palms, you would risk the product flowing out from your fingers since it’s literally as fluid as plain water.


A bright blue serum!

I usually use this product in the daytime as I’m using retinol products at night. The important thing to note is that you MUST NOT use an acid toner before using this serum as the acids will destroy the potency of the copper peptides. However, this was in no way communicated on the box or the instructions anywhere. I only discovered this when I was reading Caroline Hiron’s interview with the founder Brandon Truaxe. I believe that this had affected my initial results as I was using acid toners in combination with this product at first. I stopped using my acid toners together with this product when I learnt of that fact. The thing is it would be fine for me to use this product on alternate days separately from my acid toners if I found that the CAIS had significant enough results for me to continue. Unfortunately, I really didn’t notice much improvement, if any at all, while I was using this serum. I don’t know if my skin just doesn’t respond to this serum or if I needed more time for this serum to work. But I mean, I’ve been using it for around 4 months and surely I should see some results?! Very disappointing overall for me! This serum is almost at its end and I’m very hesitant about repurchasing. Does anybody reading my blog have better results than me? Let me know!

How does the NIOD MMHC fare?

The NIOD MMHC serum combines 12 forms of hyaluronic compounds in a peptide-charged delivery system to offer hydration and to help skin surface look plump, comfortable and uniform. This serum is slightly more viscous in texture and I usually just place it my palms, spread it and apply it all over my face. I noticed that it has a slightly weird smell of bread rolls (?!) and I think it should be due to the inclusion of yeast extract in its formulae. However the smell dissipates quite fast (thankfully!) and you should not be smelling it on your face the whole day.


A slightly viscous serum that smells of bread!

I think that this product is a really hydrating serum that works exactly as advertised. It sinks in quite nicely without any tacky finish, hydrates my skin perfectly and leaves it plump and smooth. There’s not much to fault about this product really (except for that darn bread roll smell!) and I would repurchase it once I’ve finished this bottle. I was informed that a next generation of the MMHC (MMHC Version 2) will be released very soon. MMHC2 will include 1.0% of direct hyaluronic acid, instead of the usual sodium salts of hyaluronic acid, and is supposed to be even more hydrating. I’m eagerly anticipating that one!

Where can you find it?

As mentioned above, I bought the products from NIOD’s offical website. CAIS retails for US$99.00 (30 ml sized) and MMHC retails for US$70.00 (30 ml sized).

Thank you for reading!

2 Comments on “Review – NIOD Copper Amino Isolate Serum 1.00% (CAIS) & Multi-Molecular Hyaluronic Complex (MMHC)

  1. Pingback: Review – NIOD Sanskrit Saponins – Engineering Beauty

  2. Pingback: Review – NIOD Multi-Molecular Hyaluronic Complex 2 (MMHC 2) – Engineering Beauty

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